BCO2 and DDX10

		BCO2	DDX10
Description		beta-carotene oxygenase 2	DEAD-box helicase 10
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus
	Molecular Function	Beta-carotene 15,15'-dioxygenase Activity Carotenoid Dioxygenase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Metal Ion Binding Beta,beta-carotene-9',10'-cleaving Oxygenase Activity	RNA Binding RNA Helicase Activity ATP Binding ATP Hydrolysis Activity
	Biological Process	Carotenoid Metabolic Process Carotene Metabolic Process Carotene Catabolic Process Xanthophyll Metabolic Process Retinoic Acid Metabolic Process Retinal Metabolic Process Regulation Of Mitochondrial Membrane Potential Regulation Of Reactive Oxygen Species Metabolic Process	RRNA Processing Anterior Head Development
Pathways		Retinoid metabolism and transport
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502) Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 20150558 31584380)	Bipolar disorder ( 34099189) Knee osteoarthritis ( 28916551) Systolic blood pressure ( 27841878)
Interacting Genes		2 interacting genes: ATM DDX10	16 interacting genes: ANTXR2 APP ARHGAP20 ARL2BP BCO2 CUL5 DES DSC3 FBXO7 HSPB2 IGFBP6 NPAT PGR PTS SIRPA SLN
Entrez ID		83875	1662
HPRD ID		12522	03138
Ensembl ID		ENSG00000197580	ENSG00000178105
Uniprot IDs		B2RCV8 Q9BYV7	Q13206
PDB IDs			2PL3
Enriched GO Terms of Interacting Partners?
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