ACOX2 and DYNLT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ACOX2	DYNLT1
Description		acyl-CoA oxidase 2	dynein light chain Tctex-type 1
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol Intracellular Membrane-bounded Organelle	Extracellular Region Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Acyl-CoA Oxidase Activity Fatty Acid Binding Protein Binding Palmitoyl-CoA Oxidase Activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase Activity Protein Homodimerization Activity Flavin Adenine Dinucleotide Binding FAD Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Positive Regulation Of Cell Death Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Lipid Homeostasis Positive Regulation Of Response To Oxidative Stress	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Beta-oxidation of pristanoyl-CoA Peroxisomal protein import Peroxisomal protein import	Neutrophil degranulation
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Systemic lupus erythematosus ( 28714469)
Interacting Genes		3 interacting genes: CLK1 DYNLT1 PEX5	57 interacting genes: ACAT2 ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 CRHBP DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 ERO1A FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PRKN PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RPS6KA2 RRAGA SDCBP SIRPA SVIL SYNJ2 TCEANC TMEM143 TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		8309	6993
HPRD ID		09037	15987
Ensembl ID		ENSG00000168306	ENSG00000146425
Uniprot IDs		Q99424	P63172
PDB IDs			5JPW
Enriched GO Terms of Interacting Partners?
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