DYSF and SAMHD1

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid, imaging technique)

		DYSF	SAMHD1
Description		dysferlin	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
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GO Annotations	Cellular Component	Endosome Early Endosome Late Endosome Plasma Membrane Integral Component Of Membrane Endocytic Vesicle T-tubule Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Centriolar Satellite Sarcolemma Extracellular Exosome	Nucleus Nucleoplasm Plasma Membrane Site Of Double-strand Break Tetraspanin-enriched Microdomain
	Molecular Function	Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding	Nucleic Acid Binding Single-stranded DNA Binding RNA Binding Ribonuclease Activity Protein Binding GTP Binding Zinc Ion Binding DGTPase Activity Triphosphoric Monoester Hydrolase Activity DGTP Binding Identical Protein Binding Deoxynucleoside Triphosphate Hydrolase Activity
	Biological Process	Plasma Membrane Repair Monocyte Activation Involved In Immune Response Macrophage Activation Involved In Immune Response Vesicle Fusion Plasma Membrane Organization T-tubule Organization Negative Regulation Of Phagocytosis Membrane Fusion	Double-strand Break Repair Via Homologous Recombination DGTP Catabolic Process Immune Response Cellular Response To DNA Damage Stimulus Deoxyribonucleotide Catabolic Process Somatic Hypermutation Of Immunoglobulin Genes Innate Immune Response Regulation Of Innate Immune Response DATP Catabolic Process Protein Homotetramerization Defense Response To Virus Negative Regulation Of Type I Interferon-mediated Signaling Pathway RNA Phosphodiester Bond Hydrolysis DNA Strand Resection Involved In Replication Fork Processing
Pathways		Smooth Muscle Contraction Smooth Muscle Contraction	Nucleobase catabolism Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Asthma ( 32296059) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Hip circumference adjusted for BMI ( 28552196 34021172) Nonalcoholic steatohepatitis-derived hepatocellular carcinoma ( 29385134) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787)	Caffeine consumption from coffee or tea ( 33287642) Height ( 28552196)
Interacting Genes		40 interacting genes: AKAP1 ANKRD1 ANXA1 ANXA2 APPL1 CAPN3 CAV3 CMYA5 COL12A1 COL6A3 DGKD DHX15 DNAJB6 EEF1A1 EEF1G FAM120A GNL3 KARS1 KIF1B MORF4L1 MYBPC1 MYBPC2 MYH3 MYOM1 MYOM2 NPHP3 OPTN OS9 PHF1 PLP1 RNF10 RNF2 SAMHD1 SGCG SLC12A6 SNAPIN TAF1 XIRP2 XRCC6 ZNF23	14 interacting genes: AAR2 ACTB APP ARAP3 DCAF1 DYSF FAM13B FBXO25 FBXO7 KIZ SUMO2 TIRAP TRIM21 XPO1
Entrez ID		8291	25939
HPRD ID		04307	08418
Ensembl ID		ENSG00000135636	ENSG00000101347
Uniprot IDs		O75923	Q59H15 Q9Y3Z3
PDB IDs		4CAH 4CAI 4IHB 4IQH 7K6B 7KRB	2E8O 3U1N 4BZB 4BZC 4CC9 4MZ7 4Q7H 4QFX 4QFY 4QFZ 4QG0 4QG1 4QG2 4QG4 4RXO 4RXP 4RXQ 4RXR 4RXS 4TNP 4TNQ 4TNR 4TNX 4TNY 4TNZ 4TO0 4TO1 4TO2 4TO3 4TO4 4TO5 4TO6 4ZWE 4ZWG 5AO0 5AO1 5AO2 5AO3 5AO4 6CM2 6DW3 6DW4 6DW5 6DW7 6DWD 6DWJ 6DWK 6TX0 6TXA 6TXC 6TXE 6TXF 6U6X 6U6Y 6U6Z 6XU1 6YOM
Enriched GO Terms of Interacting Partners?
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