LZTR1 and ZNF451

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		LZTR1	ZNF451
Description		leucine zipper like transcription regulator 1	zinc finger protein 451
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane	Nucleus PML Body
	Molecular Function	Protein Binding Small GTPase Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction	Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		55 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 GABARAPL2 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RIT1 RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	34 interacting genes: AR CALCOCO2 CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A KLHL40 LZTR1 MID2 OPLAH PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUV39H1 UBC UBE2I ZBED1 ZNF467
Entrez ID		8216	26036
HPRD ID		08992	10332
Ensembl ID		ENSG00000099949	ENSG00000112200
Uniprot IDs		A0A384NL67 Q8N653	B4DYS2 Q96JY2 Q9Y4E5
PDB IDs			5D2M
Enriched GO Terms of Interacting Partners?
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