CANX and CD3D

Number of citations of the paper that reports this interaction (PubMedID 8278814)
69

Data Source:
HPRD (in vitro, in vivo)

		CANX	CD3D
Description		calnexin	CD3d molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Smooth Endoplasmic Reticulum Rough Endoplasmic Reticulum Ribosome Membrane Axon Dendrite Cytoplasm Protein-containing Complex Melanosome Neuronal Cell Body Dendritic Spine Mitochondria-associated Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Active Zone Membrane	Cytoplasm Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Clathrin-coated Endocytic Vesicle Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Apolipoprotein Binding Ionotropic Glutamate Receptor Binding Unfolded Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Protein Folding Aging Protein Secretion Viral Protein Processing Ubiquitin-dependent ERAD Pathway Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis	Adaptive Immune Response Cell Surface Receptor Signaling Pathway Positive Thymic T Cell Selection
Pathways		Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate	Muromonab Blinatumomab
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Lymphocyte counts ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 32888494 27863252)	Pulse pressure ( 27841878)
Interacting Genes		48 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 NUTF2 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR	12 interacting genes: AP2M1 CANX CD247 CD3E CD3G CD8A CD8B HERPUD1 KCNA3 SGTB TRA TRB
Entrez ID		821	915
HPRD ID		00252	01730
Ensembl ID		ENSG00000127022	ENSG00000167286
Uniprot IDs		P27824	B0YIY4 P04234
PDB IDs			1XIW 6JXR
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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