CHAF1B and CBR1

		CHAF1B	CBR1
Description		chromatin assembly factor 1 subunit B	carbonyl reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Xenobiotic Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs			Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)	Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)
Interacting Genes		15 interacting genes: APP ASF1A ASF1B CBR1 CDK1 CDK2 CHAF1A H3-4 H3C6 MAL2 PGM1 PRELP RBBP4 SETD4 SUMO2	13 interacting genes: AGTR1 CHAF1B ERBB2 ERCC8 HRK HTR2B JAK1 LZTS1 OGT PRKAR2B PTPRF UBC VHL
Entrez ID		8208	873
HPRD ID		03147	00267
Ensembl ID		ENSG00000159259	ENSG00000159228
Uniprot IDs		Q13112	A0A384NL53 P16152
PDB IDs			1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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