NUAK2 and GRIPAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NUAK2	GRIPAP1
Description		NUAK family kinase 2	GRIP1 associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytosol Axon Dendrite Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Blood Microparticle Postsynaptic Recycling Endosome Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Actin Cytoskeleton Organization Intracellular Signal Transduction Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process	Biological_process Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Regulation Of Modification Of Synaptic Structure
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 29403010) Meat-related diet ( 32066663) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Eosinophil percentage of white cells ( 32888494)
Interacting Genes		7 interacting genes: ACVR1 APP GRIPAP1 LATS1 SMAD2 SMAD4 TGFBR1	73 interacting genes: AARD ANKRD11 ARL15 ATG5 BYSL CASP3 CBX8 CCDC103 CCDC185 CCDC187 CCNB3 CCNH CCNT1 CDC37 CEP57L1 CFAP53 CWF19L2 DAXX DISC1 DUSP26 EHHADH ELOA ENKD1 FAM161A FAM50B FAM90A1 FXR1 GAS8 GPR173 GRIA1 GRIP1 GRM7 HDAC4 HSPB1 ING4 ING5 LNX1 MAGED4B MAP3K1 MEOX2 MFAP1 MLLT6 NUAK2 PIBF1 PKP2 PPP1R18 PRPF18 PSMB1 RAB4A RCOR3 SMAD2 SMARCE1 SMURF1 SNAPC5 SNW1 SPP1 STAP1 TBC1D30 TCEA2 TCP10L TEPSIN TES TRAF2 TSGA10IP TSHZ2 TSNAX TTC23 USP2 ZMAT2 ZNF219 ZNF250 ZNF35 ZNF835
Entrez ID		81788	56850
HPRD ID		12172	02325
Ensembl ID		ENSG00000163545	ENSG00000068400
Uniprot IDs		B4E0Y5 Q9H093	Q4V328
PDB IDs
Enriched GO Terms of Interacting Partners?
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