COIL and DHX16

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (proximity labelling technology, two hybrid)
HPRD (two hybrid)

		COIL	DHX16
Description		coilin	DEAH-box helicase 16
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Spliceosomal SnRNP Assembly	MRNA Splicing, Via Spliceosome RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 18391951)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		84 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR1 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 OGT PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277	10 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 SNRNP27 SNRNP40 XAB2
Entrez ID		8161	8449
HPRD ID		02605	04555
Ensembl ID		ENSG00000121058	ENSG00000204560
Uniprot IDs		P38432	A0A1U9X7L7 B4DZ28 O60231 Q5SQH4
PDB IDs			5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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