ACTL8 and CERT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ACTL8	CERT1
Description		actin like 8	ceramide transporter 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Dynactin Complex	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Kinase Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Epithelial Cell Differentiation	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Population Proliferation Phosphorylation Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Mitochondrion Morphogenesis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 31219225) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		2 interacting genes: CERT1 UBC	18 interacting genes: ACTL8 AQP2 ARL6IP1 BSND CBS COL4A3 CSNK1G2 FTSJ1 ITGB3BP MINAR1 PM20D2 POM121 REEP6 RTN3 RTN4 SMU1 STX2 TGM2
Entrez ID		81569	10087
HPRD ID		11274	05246
Ensembl ID		ENSG00000117148	ENSG00000113163
Uniprot IDs		Q9H568	A0A024RAJ5 A0A2R8Y7C5 Q9Y5P4
PDB IDs			2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81
Enriched GO Terms of Interacting Partners?
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