TMX1 and SULT2A1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TMX1	SULT2A1
Description		thioredoxin related transmembrane protein 1	sulfotransferase family 2A member 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytoplasm Cytosol
	Molecular Function	Protein Binding Disulfide Oxidoreductase Activity	Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Bile-salt Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Response To Endoplasmic Reticulum Stress	Ethanol Catabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Catabolic Process Bile Acid Catabolic Process Thyroid Hormone Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways			Cytosolic sulfonation of small molecules PPARA activates gene expression
Drugs			Adenosine 3',5'-diphosphate Aetiocholanolone Mercuric iodide
Diseases
GWAS		Cancer ( 29299148) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)	Apolipoprotein A1 levels ( 32203549) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 30072576) Cleft palate ( 30452639) Dehydroepiandrosterone sulphate levels ( 21533175) Estradiol levels ( 34255042) Gallstone disease ( 30504769 27094239) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum metabolite levels ( 33031748 23093944) Sex hormone levels ( 26014426) Triglyceride levels ( 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		13 interacting genes: BCL2L2 CCR1 CDC42 DNAAF2 FAS FKBP8 GET3 GIMAP1 GIMAP5 LHFPL5 PMP22 SPI1 SULT2A1	8 interacting genes: DPYD GDF15 NIF3L1 PRDX4 STAT3 STK3 SULT1B1 TMX1
Entrez ID		81542	6822
HPRD ID		15590	00502
Ensembl ID		ENSG00000139921	ENSG00000105398
Uniprot IDs		Q9H3N1	A8K015 Q06520
PDB IDs		1X5E	1EFH 1J99 1OV4 2QP3 2QP4 3F3Y 4IFB
Enriched GO Terms of Interacting Partners?
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