TCL1A and TRMT61A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TCL1A	TRMT61A
Description		TCL1 family AKT coactivator A	tRNA methyltransferase 61A
Image
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Protein-containing Complex	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity	Protein Binding MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Apoptotic Process Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Serine/threonine Kinase Activity	TRNA Methylation MRNA Methylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Adverse response to aromatase inhibitors ( 20876420) Mosaic loss of chromosome Y ( 27064253) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Plateletcrit ( 32888494) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)
Interacting Genes		38 interacting genes: AKT1 AKT2 AKT3 ATM CADPS CALCOCO2 CARD9 CASP8AP2 CCDC13 CEP55 DDIT4L DNMT3A FLACC1 GOLGA2 H2AW INCA1 LNX1 LNX2 LSM3 NFKBIA NFKBID NIF3L1 NTAQ1 PPP1R13B PRTFDC1 REL TAX1BP1 TCF4 TEPSIN TNKS TP53BP2 TRAF1 TRAF2 TRMT61A TTC33 TXLNA TXLNB WDR47	10 interacting genes: ADSS1 AHNAK2 CLBA1 COA8 IGHV5-78 PLD4 TCL1A TDRD9 TMEM121 TRMT6
Entrez ID		8115	115708
HPRD ID		01744	08810
Ensembl ID		ENSG00000100721	ENSG00000166166
Uniprot IDs		A0A024R6G5 P56279	A0A024R6Q2 Q96FX7
PDB IDs		1JSG	5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?