ASXL3 and ZBTB14

		ASXL3	ZBTB14
Description		ASXL transcriptional regulator 3	zinc finger and BTB domain containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PR-DUB Complex	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	DNA Binding Chromatin Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Animal Organ Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Heart Valve Development Cardiac Septum Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Intake of total sugars ( 31005972) Multiple system atrophy (pathologically confirmed) ( 27629089) Neurociticism ( 29500382) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Pulmonary function ( 23932459) Systolic blood pressure ( 30578418)	Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)
Interacting Genes		2 interacting genes: CLK1 ZBTB14	60 interacting genes: AP1M1 AP4B1 ASXL3 ATP5PO ATRIP B4GALT6 BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 COLEC12 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 ITGB7 KAT5 KCNAB3 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 PIN1 PLAGL1 PNKP POLR2L PRMT1 PTPN2 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SLC4A1 SNRPB2 SYT16 TCEANC TM9SF1 TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		80816	7541
HPRD ID		11158	03674
Ensembl ID		ENSG00000141431	ENSG00000198081
Uniprot IDs		Q9C0F0	B2R850 O43829
PDB IDs
Enriched GO Terms of Interacting Partners?
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