TRAF3IP3 and ATG16L1

Number of citations of the paper that reports this interaction (PubMedID 27273576)
26

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TRAF3IP3	ATG16L1
Description		TRAF3 interacting protein 3	autophagy related 16 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrial Outer Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Membrane	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane Vacuole-isolation Membrane Contact Site
	Molecular Function	Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding
	Biological Process		Autophagosome Assembly Positive Regulation Of Autophagy Protein Transport Macroautophagy Protein Localization To Phagophore Assembly Site Negative Stranded Viral RNA Replication Protein Lipidation Involved In Autophagosome Assembly Xenophagy
Pathways			Macroautophagy Macroautophagy
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Orofacial clefts ( 33137956) Red blood cell count ( 32888494 27863252) Worry too long after an embarrassing experience ( 29500382)	Bilirubin levels ( 31801373 31319653 32084209) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		47 interacting genes: ATG16L1 CBARP CCDC136 CCDC138 CCDC88B CCNC CDCA7L CEP68 CEP70 COQ9 CPLX4 CREB3L3 EBAG9 EMD EVI2B FAM209A FATE1 GOLGA6L9 GOLM2 GORAB GRAMD2A KASH5 KIR2DL3 KRT27 L3MBTL3 LIME1 LRRC25 MFF MINAR1 NDEL1 OSBPL3 PLEKHO1 PSTPIP1 RACGAP1 RIC3 RILPL1 SP100 STMN4 STX1A STX4 TFIP11 TMEM139 TRAF3 TRIM36 WAC ZNRD2 ZRANB1	18 interacting genes: APP ATG5 C3 CSNK2A1 CSNK2A2 DEDD2 GAN GIGYF2 NOD1 NOD2 OPTN PLD3 RAB33A RAB33B SCAP SETD7 TRAF3IP3 ZFP36
Entrez ID		80342	55054
HPRD ID		16305	16498
Ensembl ID		ENSG00000009790	ENSG00000085978
Uniprot IDs		B1AJU2 B3KWQ9 Q9Y228	A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5
PDB IDs			4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX
Enriched GO Terms of Interacting Partners?
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