DNAJC5 and SYT12

Number of citations of the paper that reports this interaction (PubMedID 29997244)
6

Data Source:
BioGRID (fluorescent resonance energy transfer)

		DNAJC5	SYT12
Description		DnaJ heat shock protein family (Hsp40) member C5	synaptotagmin 12
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Plasma Membrane Integral Component Of Membrane Synaptic Vesicle Membrane Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	Protein Binding ATP-dependent Protein Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding
	Biological Process	Exocytosis Synaptic Vesicle Exocytosis Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Neurotransmitter Secretion Spontaneous Exocytosis Of Neurotransmitter Long-term Synaptic Potentiation Cellular Response To Calcium Ion
Pathways		Neutrophil degranulation GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea	Neurexins and neuroligins
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)	Bipolar disorder ( 21926972) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		49 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CD2 CFTR CGB5 CLCN3 ERC1 FAS FCHO1 GRM8 HBA2 KHDC4 LIN7A LIN7C NECAP1 NRXN3 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7	1 interacting genes: DNAJC5
Entrez ID		80331	91683
HPRD ID		08539	07337
Ensembl ID		ENSG00000101152	ENSG00000173227
Uniprot IDs		Q6AHX3 Q9H3Z4	B0AZL9 Q8IV01 Q8NDM9
PDB IDs		2N04 2N05
Enriched GO Terms of Interacting Partners?
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