EFHC2 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EFHC2	L3MBTL2
Description		EF-hand domain containing 2	L3MBTL histone methyl-lysine binding protein 2
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GO Annotations	Cellular Component	Microtubule Axoneme Ciliary Basal Body Mitotic Spindle	Nucleus Nucleoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Alpha-tubulin Binding	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Regulation Of Neuron Projection Development Cilium-dependent Cell Motility Cellular Response To Leukemia Inhibitory Factor	Chromatin Organization Negative Regulation Of Transcription, DNA-templated
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Glaucoma (primary open-angle) ( 33627673) Mean arterial pressure ( 29403010)	Adventurousness ( 30643258) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		100 interacting genes: - AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 USP2 ZBTB16 ZFHX3 ZZZ3	53 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 CYB5R3 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAFA5 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 TUBGCP6 XPNPEP3 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829
Entrez ID		80258	83746
HPRD ID		06540	13954
Ensembl ID		ENSG00000183690	ENSG00000100395
Uniprot IDs		Q5JST6	A0A0S2Z5X6 Q969R5
PDB IDs		2Z13 2Z14	2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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