CCDC92 and CHGB

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC92	CHGB
Description		coiled-coil domain containing 92	chromogranin B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Centriole Intracellular Membrane-bounded Organelle	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	Protein Binding Identical Protein Binding	Hormone Activity Protein Binding
	Biological Process		Signal Transduction
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body shape index ( 34021172) Coronary artery disease ( 29212778 28714974) Hand grip strength ( 29691431) HDL cholesterol ( 20686565) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 31453325) Hip circumference adjusted for BMI ( 34021172) Hip circumference variance ( 31453325) Hip index ( 34021172) Lymphocyte counts ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 20686565) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172) Waist circumference variance ( 31453325) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971 30389748) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 32888494 27863252)	Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		15 interacting genes: CEP76 CHGB COG6 DISC1 FHL2 FXR1 FXR2 GOLGA2 PLEKHA5 PSMD8 TCTN2 TP53BP2 TRIM27 TRIML2 UBC	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAFAZZIN TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		80212	1114
HPRD ID		16919	07512
Ensembl ID		ENSG00000119242	ENSG00000089199
Uniprot IDs		Q53HC0	P05060
PDB IDs
Enriched GO Terms of Interacting Partners?
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