ELOVL7 and ADGRE2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ELOVL7	ADGRE2
Description		ELOVL fatty acid elongase 7	adhesion G protein-coupled receptor E2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane
	Molecular Function	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)	Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1	19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80
Entrez ID		79993	30817
HPRD ID		18700	07308
Ensembl ID		ENSG00000164181	ENSG00000127507
Uniprot IDs		A1L3X0 D6RHD0	A0JNV7 Q9UHX3
PDB IDs		6Y7F	2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?
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