TUSC3 and BMI1

Number of citations of the paper that reports this interaction (PubMedID 19451220)
36

Data Source:
BioGRID (pull down)

		TUSC3	BMI1
Description		tumor suppressor candidate 3	BMI1 proto-oncogene, polycomb ring finger
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Oligosaccharyltransferase Complex	Ubiquitin Ligase Complex Heterochromatin Nucleus Nucleoplasm Cytosol Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Magnesium Ion Transmembrane Transporter Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Zinc Ion Binding RING-like Zinc Finger Domain Binding Ubiquitin-protein Transferase Activator Activity Promoter-specific Chromatin Binding
	Biological Process	Protein N-linked Glycosylation Magnesium Ion Transport Protein N-linked Glycosylation Via Asparagine Cognition Transmembrane Transport Magnesium Ion Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Methylation Humoral Immune Response Segment Specification Brain Development Regulation Of Gene Expression Histone Acetylation Rostrocaudal Neural Tube Patterning Hemopoiesis Positive Regulation Of B Cell Proliferation Positive Regulation Of Immature T Cell Proliferation In Thymus Histone H2A-K119 Monoubiquitination Negative Regulation Of Gene Expression, Epigenetic Somatic Stem Cell Division Positive Regulation Of Fibroblast Proliferation Embryonic Skeletal System Morphogenesis Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Interleukin-1 Cellular Response To Dexamethasone Stimulus Regulation Of Adaxial/abaxial Pattern Formation Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Asparagine N-linked glycosylation Miscellaneous transport and binding events Maturation of spike protein	Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intelligence ( 22449649) Metabolite levels ( 23823483) Methamphetamine dependence ( 23594818) Prudent dietary pattern ( 28644415) Pulmonary function decline ( 22424883) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to SSRI in MDD or openness ( 29559929)	Prostate-specific antigen levels ( 28139693)
Interacting Genes		2 interacting genes: BMI1 PPP1CA	42 interacting genes: CASC9 CBX8 CEP126 CSNK2B E2F6 FOXS1 H2AC18 H2AC20 H2AC4 H2AX H3-4 HSF2BP IMMT KAT5 KMT2A LRIF1 MAPK14 MLLT1 MUC1 NDEL1 PCBP2-OT1 PCGF3 PCGF6 PGR PHC1 PHC2 PTN RING1 RNF114 RNF2 RRM1 SOCS2 TRIM27 TUSC3 UBE2D2 UBE2D3 UBE2I USP11 USP15 VPS11 WHRN ZBTB16
Entrez ID		7991	648
HPRD ID		03228	01277
Ensembl ID		ENSG00000104723	ENSG00000168283
Uniprot IDs		Q13454	P35226
PDB IDs		4M8G 4M90 4M91 4M92	2H0D 2NA1 3RPG 4R8P 5FR6
Enriched GO Terms of Interacting Partners?
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