ZNF408 and MRRF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF408	MRRF
Description		zinc finger protein 408	mitochondrial ribosome recycling factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Ribosomal Large Subunit Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Translation Ribosome Disassembly
Pathways			Mitochondrial translation termination
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)
Interacting Genes		84 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CREB3L1 CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1	11 interacting genes: AGTRAP APP BANP CDK5RAP2 CMTM5 FAM9B FHL3 KRT40 SYP WIPI2 ZNF408
Entrez ID		79797	92399
HPRD ID		18338	06856
Ensembl ID		ENSG00000175213	ENSG00000148187
Uniprot IDs		B4DXY4 Q9H9D4	Q96E11
PDB IDs			6NU2 6ZS9
Enriched GO Terms of Interacting Partners?
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