TTLL7 and LMO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TTLL7	LMO4
Description		tubulin tyrosine ligase like 7	LIM domain only 4
Image
GO Annotations	Cellular Component	Cytosol Microtubule Cilium Dendrite Perikaryon	Transcription Regulator Complex Cell Leading Edge RNA Polymerase II Transcription Regulator Complex
	Molecular Function	ATP Binding Tubulin Binding Alpha-tubulin Binding Beta-tubulin Binding Tubulin-glutamic Acid Ligase Activity	Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Nervous System Development Protein Polyglutamylation Cell Differentiation	Neural Tube Closure Ventricular Septum Development Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease ( 20061627) Body mass index ( 25673413) General risk tolerance (MTAG) ( 30643258) Mental health study participation (completed survey) ( 31263887) Mild influenza (H1N1) infection ( 26379185) Obesity-related traits ( 23251661) Response to taxane treatment (docetaxel) ( 23006423) Tenofovir clearance in HIV infection ( 26148204) Time-dependent creatinine clearance change response to tenofovir treatment in HIV infection (time and treatment arm interaction) ( 26148204) Toenail selenium levels ( 25343990)	Academic attainment (English) ( 33594131) Age at first sexual intercourse ( 34211149) Alanine aminotransferase levels ( 33547301) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Aspartate aminotransferase levels ( 33547301) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		3 interacting genes: APP LMO4 ZDHHC17	131 interacting genes: AARD ABI2 ADAMTSL4 AMOT AMOTL2 ARNT2 BANP BBS2 BCAS2 BIRC7 BRCA1 C12orf40 CALCOCO2 CCDC102B CCDC120 CEP170P1 COG6 CRNN CRYBB2 CSNK2B CTBP2 CYSRT1 DDB1 DEAF1 DES DYNC1H1 ECM1 ERCC6L EXOSC8 FAM228A FHL3 GABPB1 GADD45A GOLGA2 GOLGA6L9 GRHL2 GSK3B HELT HGS HSF2BP ID3 IKZF1 IKZF3 ITSN1 KANK2 KATNBL1 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT33B KRT34 KRT38 KRT39 KRT40 KRT74 KRT75 KRT76 KRTAP11-1 KRTAP3-1 KYNU L3MBTL3 LASP1 LDB1 LDB2 LMO2 LZTS1 MCCD1 MERTK METTL27 MID2 MTA1 MTUS2 MYOD1 MYOZ3 N4BP3 NFKBID NFYC NHLH1 NME4 NONO NRF1 PDE4DIP PELO PER2 PITPNB PLK1 PPARG PPP1R32 QRICH1 RBAK RBBP8 RBPMS RCN1 RNF8 ROPN1 RPS6KA6 RSPH6A SEC24D SLC15A2 SMAD4 SMAD9 STAT5B SUOX TCF21 TCF4 TEX14 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TRAF5 TRIM27 TRIM54 TSEN15 TTLL7 UBQLN2 VMAC VPS52 WASHC1 ZBTB43 ZMYND12 ZNF135 ZNF202 ZNF213 ZNF397 ZNF410 ZNF467 ZNF675
Entrez ID		79739	8543
HPRD ID		08013	09122
Ensembl ID		ENSG00000137941	ENSG00000143013
Uniprot IDs		Q6ZT98	P61968
PDB IDs		4YLR 4YLS	2L4Z
Enriched GO Terms of Interacting Partners?
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