ZC2HC1C and NOXA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZC2HC1C	NOXA1
Description		zinc finger C2HC-type containing 1C	NADPH oxidase activator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol NADPH Oxidase Complex
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding
	Biological Process		Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways			RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Refractive error ( 32231278)	Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		80 interacting genes: ACTN2 ANKS1A ARMC7 BANP BICD2 BYSL C19orf54 CABP5 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC85B CCDC88B CIB3 CLIC3 CRACR2A DDX6 EMILIN1 ENKD1 FAM90A1 FBXO7 FGFR1OP2 FSD2 GFAP GOLGA1 GOLGA2 GOLGA6A GPRASP2 HOOK2 HSF2BP KASH5 KAT5 KATNBL1 KIF9 KRT15 KRT20 KRT40 LMNA LMNB2 LZTS2 MAPK9 MAPRE3 MID2 MTUS2 NCKIPSD NDEL1 NDOR1 NEK6 NOXA1 NTAQ1 OSGIN1 PFDN5 PIBF1 PNMA1 POLR1C PRKAB2 PSTPIP1 RABGEF1 RAD51D RINT1 SFN SIKE1 SMARCD1 SORBS3 SPAG5 TFIP11 TNPO2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM55 TRIM63 UBASH3A VPS52 ZNF655 ZNF76	57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID		79696	10811
HPRD ID		16607	17644
Ensembl ID		ENSG00000119703	ENSG00000188747
Uniprot IDs		A0A024R6E6 H0YE08 J3KMY6 Q53FD0	Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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