TUT7 and MIRLET7C

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		TUT7	MIRLET7C
Description		terminal uridylyl transferase 7	microRNA let-7c
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Extracellular Space Nucleus Cytoplasm Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Nucleotidyltransferase Activity MiRNA Binding RNA Uridylyltransferase Activity Uridylyltransferase Activity	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Oocyte Maturation Negative Regulation Of Transposition, RNA-mediated MiRNA Metabolic Process Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process RNA 3' Uridylation Polyuridylation-dependent MRNA Catabolic Process	Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-8 Production Gene Silencing By MiRNA Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT
Pathways		Deadenylation of mRNA
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: APP MIR138-2 MIR25 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17	96 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CHERP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		79670	406885
HPRD ID		11697
Ensembl ID		ENSG00000083223	ENSG00000199030
Uniprot IDs		Q5VYS8 Q96KX5 X6R3Q3
PDB IDs		5W0B 5W0M 5W0N 5W0O
Enriched GO Terms of Interacting Partners?
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