YIPF2 and SPCS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		YIPF2	SPCS1
Description		Yip1 domain family member 2	signal peptidase complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Integral Component Of Membrane Transport Vesicle Late Endosome Membrane	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Small GTPase Binding	Molecular_function Protein Binding Peptidase Activity
	Biological Process	Vesicle-mediated Transport	Signal Peptide Processing Proteolysis Virion Assembly Viral Protein Processing Protein Targeting To ER
Pathways			SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Feeling worry ( 29500382) Schizophrenia ( 28991256 25056061 29483656 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		24 interacting genes: AQP6 CREB3 ERGIC3 FATE1 FFAR2 GPR42 HSD17B13 LEPROTL1 MFSD14B PGRMC2 RNF185 RNF5 SHISAL2A SLC10A6 SLC30A2 SLC39A3 SPCS1 STING1 SYPL2 TMEM143 TMEM14B TMX2 TVP23B YIPF6	10 interacting genes: AQP2 FIS1 FXYD6-FXYD2 NAALAD2 RPRM SLC22A2 SLC25A46 TMEM74 UBXN8 YIPF2
Entrez ID		78992	28972
HPRD ID		11332	07155
Ensembl ID		ENSG00000130733	ENSG00000114902
Uniprot IDs		A0A024R7E1 K7ENM8 Q9BWQ6	Q9Y6A9
PDB IDs
Enriched GO Terms of Interacting Partners?
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