CACNB1 and REM1

Number of citations of the paper that reports this interaction (PubMedID 14623965)
81

Data Source:
HPRD (in vivo)

		CACNB1	REM1
Description		calcium voltage-gated channel auxiliary subunit beta 1	RRAD and GEM like GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Sarcolemma Synapse	Plasma Membrane
	Molecular Function	Voltage-gated Calcium Channel Activity Protein Binding High Voltage-gated Calcium Channel Activity	GTPase Activity Calcium Channel Regulator Activity Calmodulin Binding GTP Binding
	Biological Process	Chemical Synaptic Transmission Neuromuscular Junction Development Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Cellular Response To Amyloid-beta	Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways		Presynaptic depolarization and calcium channel opening NCAM1 interactions Phase 0 - rapid depolarisation Phase 2 - plateau phase
Drugs		Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Ibutilide Amlodipine Nimodipine Spironolactone Magnesium sulfate Levomenthol Ethanol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Azelnidipine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS		Asthma ( 31619474) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
Interacting Genes		8 interacting genes: APP ATN1 CACNA1A CTBP2 DYNLL1 NEDD4L REM1 SRPK1	7 interacting genes: CACNB1 CACNB2 CACNB4 YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		782	28954
HPRD ID		11743	15237
Ensembl ID		ENSG00000067191	ENSG00000088320
Uniprot IDs		Q02641	O75628
PDB IDs			2NZJ
Enriched GO Terms of Interacting Partners?
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