DDR1 and SNRNP40

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DDR1	SNRNP40
Description		discoidin domain receptor tyrosine kinase 1	small nuclear ribonucleoprotein U5 subunit 40
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Exosome	Nucleoplasm U5 SnRNP Sno(s)RNA-containing Ribonucleoprotein Complex Cytosol Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding Collagen Binding ATP Binding Protein Tyrosine Kinase Collagen Receptor Activity Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Cell-matrix Adhesion Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Embryo Implantation Lactation Negative Regulation Of Cell Population Proliferation Regulation Of Extracellular Matrix Disassembly Smooth Muscle Cell Migration Positive Regulation Of Kinase Activity Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Ear Development Wound Healing, Spreading Of Cells Protein Autophosphorylation Branching Involved In Mammary Gland Duct Morphogenesis Mammary Gland Alveolus Development Smooth Muscle Cell-matrix Adhesion Axon Development Neuron Projection Extension	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing
Pathways		Non-integrin membrane-ECM interactions	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs		Imatinib Fostamatinib Pralsetinib
Diseases
GWAS		Age-related macular degeneration ( 23455636) Arterial stiffness index ( 31235810) Autism spectrum disorder or schizophrenia ( 28540026) HIV-1 control ( 20041166) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Malaria ( 31844061) Microalbuminuria in type 1 diabetes ( 31537649) Response to hepatitis B vaccine ( 29534301) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Schizophrenia ( 30285260) Serum alkaline phosphatase levels ( 33547301) Smoking initiation (ever regular vs never regular) ( 30679032) Takayasu arteritis ( 25604533) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Ulcerative colitis ( 20848476) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Alcohol dependence ( 23455491) Body mass index ( 26426971 29615537)
Interacting Genes		20 interacting genes: BEND5 BRD2 COL11A1 COL2A1 COL3A1 COL5A2 ERBB2 FRS2 MAPK6 NCK2 NUDT3 PLCG1 PTPN11 RGS2 SHC1 SNAPIN SNRNP40 TM4SF1 TTR UBQLN2	5 interacting genes: ACP5 APP DDR1 DHX16 SNRNP200
Entrez ID		780	9410
HPRD ID		02678	08481
Ensembl ID		ENSG00000204580	ENSG00000060688
Uniprot IDs		A0A024RCJ0 A0A024RCL1 A0A024RCQ1 A0A0A0MSX3 Q08345 Q96T61 Q96T62	A0MNP2 Q96DI7
PDB IDs		3ZOS 4AG4 4BKJ 4CKR 5BVK 5BVN 5BVO 5BVW 5FDP 5FDX 6BRJ 6BSD 6FEW 6FEX 6FIL 6FIN 6FIO 6FIQ 6GWR 6HP9 6Y23 7BCM 7BE6	3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6ZYM 7ABG 7ABI
Enriched GO Terms of Interacting Partners?
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