ZYX and NME5

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		ZYX	NME5
Description		zyxin	NME/NM23 family member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle	Cellular_component Extracellular Region Cilium Sperm Flagellum
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Nucleoside Diphosphate Kinase Activity Protein Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Spermatogenesis Spermatid Development Nucleoside Metabolic Process Ventricular System Development Cilium Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)	Atrial fibrillation ( 29892015) Autism spectrum disorder or schizophrenia ( 28540026) Carboplatin disposition in epthelial ovarian cancer ( 29367611)
Interacting Genes		35 interacting genes: ACTN1 ATXN1 BSPRY CASS4 ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B	4 interacting genes: CEP76 DYDC1 DYDC2 ZYX
Entrez ID		7791	8382
HPRD ID		03592	04655
Ensembl ID		ENSG00000159840	ENSG00000112981
Uniprot IDs		Q15942 Q96AF9	A0A0S2Z4L9 P56597
PDB IDs
Enriched GO Terms of Interacting Partners?
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