ZBTB17 and HK3

Number of citations of the paper that reports this interaction (PubMedID 11068878)
5

Data Source:
HPRD (two hybrid, in vitro)

		ZBTB17	HK3
Description		zinc finger and BTB domain containing 17	hexokinase 3
Image
GO Annotations	Cellular Component	Nucleoplasm Protein-containing Complex Protein-DNA Complex	Extracellular Region Mitochondrion Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Glucokinase Activity Hexokinase Activity Protein Binding ATP Binding Glucose Binding Fructokinase Activity Mannokinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Gastrulation With Mouth Forming Second Regulation Of Transcription By RNA Polymerase II Ectoderm Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle	Cellular Glucose Homeostasis Fructose 6-phosphate Metabolic Process Glycolytic Process Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Canonical Glycolysis
Pathways		XBP1(S) activates chaperone genes	Neutrophil degranulation Glycolysis
Drugs
Diseases
GWAS		Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Erectile dysfunction ( 30583798) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Idiopathic dilated cardiomyopathy ( 21459883)	Uterine fibroids ( 30194396) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		29 interacting genes: BCL6 CDKN2B CREBBP DIS3 DNMT3A E2F6 EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 HSPB1 IRF8 ITGB5 MAX MSX2 MTHFR MYC MYCN PGR RERE TMPRSS11A TOPBP1 TRIM55 TRIM63 ZBTB7C ZBTB8A	12 interacting genes: ATF4 GRN HPGDS IGFBP4 LEP LRP2 MEOX2 MITF PPP2CB PTGDS STC2 ZBTB17
Entrez ID		7709	3101
HPRD ID		04968	00806
Ensembl ID		ENSG00000116809	ENSG00000160883
Uniprot IDs		Q13105 Q53EM1	A0A024R7R1 P52790
PDB IDs		2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2N25 2N26 2Q81 3M52 4U2M 4U2N 5ION	3HM8
Enriched GO Terms of Interacting Partners?
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