UQCRH and NDFIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UQCRH	NDFIP2
Description		ubiquinol-cytochrome c reductase hinge protein	Nedd4 family interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III	Golgi Membrane Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Multivesicular Body Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquinol-cytochrome-c Reductase Activity	Protein Binding WW Domain Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Proton Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Negative Regulation Of Gene Expression Metal Ion Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Transport
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172)	Bullous pemphigoid ( 34011352) Leisure-time exercise behaviour (age-stratified) ( 30102679) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Pancreatic cancer ( 20686608) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		7 interacting genes: ARL8A FAM189B NDFIP1 NDFIP2 NPM1 PRRG1 RNF24	13 interacting genes: ALKBH2 AQP2 ITCH LYN NEDD4 NEDD4L POU4F1 RBM26 SLITRK6 SMURF1 SPRY2 UQCRH WWP2
Entrez ID		7388	54602
HPRD ID		15629	17629
Ensembl ID		ENSG00000173660	ENSG00000102471
Uniprot IDs		P07919 Q567R0	B4DGY6 Q9NV92
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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