UQCRB and HPCA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		UQCRB	HPCA
Description		ubiquinol-cytochrome c reductase binding protein	hippocalcin
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III	Cytoplasm Cytosol Extrinsic Component Of Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Glutamatergic Synapse
	Molecular Function	Protein Binding	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration	Brain Development Calcium-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Activation Of Phospholipase D Activity Positive Regulation Of Adenylate Cyclase Activity Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Cellular Response To Monosodium Glutamate Response To Aroclor 1254
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Huntington's disease progression ( 28642124)	Daytime nap ( 33568662)
Interacting Genes		9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7	28 interacting genes: APC BMP8B C1QTNF2 CKMT1A CKMT1B CREM CSF3R DPYD DTX2 E2F2 GATA5 IL36RN MLLT10 MYDGF NAIP NDC80 NMT1 NUDC PRR35 RAE1 RUNX3 SLC16A3 TEPSIN TMEM54 TNFRSF8 TUBA4A UQCRB VWC2
Entrez ID		7381	3208
HPRD ID		11770	00811
Ensembl ID		ENSG00000156467	ENSG00000121905
Uniprot IDs		P14927	P84074
PDB IDs		5XTE 5XTH 5XTI	5G4P 5G58 5M6C
Enriched GO Terms of Interacting Partners?
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