TRPC3 and TRPC7

Number of citations of the paper that reports this interaction (PubMedID 12032305)
231

Data Source:
BioGRID (fluorescent resonance energy transfer)

		TRPC3	TRPC7
Description		transient receptor potential cation channel subfamily C member 3	transient receptor potential cation channel subfamily C member 7
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex	Nuclear Envelope Cis-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Calcium Ion Transport Manganese Ion Transport Single Fertilization Phototransduction Positive Regulation Of Calcium Ion Transport Into Cytosol Response To ATP Regulation Of Cytosolic Calcium Ion Concentration Response To Calcium Ion Calcium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	Manganese Ion Transport Single Fertilization Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport
Pathways		Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling MECP2 regulates neuronal receptors and channels	Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS		Asthma ( 31959851 34103634) Celiac disease and Rheumatoid arthritis ( 26546613) Emphysema imaging phenotypes ( 26030696) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Rosacea symptom severity ( 29771307)	Body fat percentage ( 31752434) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Sleep duration (short sleep) ( 30846698)
Interacting Genes		21 interacting genes: BBS7 CALM1 FKBP1A GNA11 ITPR1 ITPR3 MX1 NAPA ORAI1 PLCB1 PLCB2 PLCB3 PLCG1 PRKCA PRKG1 SLC8A1 STX3 TRPC1 TRPC6 TRPC7 VAMP2	4 interacting genes: ITPR3 MX1 TRPC3 TRPC6
Entrez ID		7222	57113
HPRD ID		15999	18228
Ensembl ID		ENSG00000138741	ENSG00000069018
Uniprot IDs		Q13507	Q9HCX4
PDB IDs		5ZBG 6CUD 6D7L 6DJS
Enriched GO Terms of Interacting Partners?
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