TPI1 and LIPT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		TPI1	LIPT1
Description		triosephosphate isomerase 1	lipoyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Triose-phosphate Isomerase Activity Protein Binding Methylglyoxal Synthase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity	Protein Binding Acyltransferase Activity Lipoyltransferase Activity
	Biological Process	Gluconeogenesis Glycolytic Process Methylglyoxal Biosynthetic Process Glycerol Catabolic Process Glyceraldehyde-3-phosphate Biosynthetic Process	Cellular Protein Modification Process Lipid Metabolic Process Protein Lipoylation Carboxylic Acid Metabolic Process
Pathways		Glycolysis Gluconeogenesis	Glyoxylate metabolism and glycine degradation
Drugs		Zinc N-Hydroxy-4-Phosphono-Butanamide 2-Phosphoglycolic Acid Phosphoglycolohydroxamic Acid 3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid 5-fluorotryptophan 2-Carboxyethylphosphonic Acid tert-butanol Dihydroxyacetone phosphate 1,4-Dithiothreitol 3-phospho-D-glyceric acid 3-(BUTYLSULPHONYL)-PROPANOIC ACID Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Lipoic acid
Diseases
GWAS		Blood protein levels ( 30072576) Refractive error ( 32231278)	Bipolar disorder ( 21926972)
Interacting Genes		17 interacting genes: APP BDKRB2 CCL11 CDKN2A CFL1 DDX24 EGFR HTR2C LIPT1 MAPK6 PCNA POT1 SETDB1 SP1 TERF1 UCHL5 YWHAQ	2 interacting genes: APP TPI1
Entrez ID		7167	51601
HPRD ID		01833	17282
Ensembl ID		ENSG00000111669	ENSG00000144182
Uniprot IDs		P60174 Q53HE2 V9HWK1	Q9Y234
PDB IDs		1HTI 1KLG 1KLU 1WYI 2IAM 2IAN 2JK2 2VOM 4BR1 4E41 4POC 4POD 4UNK 4UNL 4ZVJ 6C2G 6D43 6NLH 6UP1 6UP5 6UP8 6UPF
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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