Description |
DNA topoisomerase I |
phosphodiesterase 10A |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
- Antipsychotic drug-induced weight gain in schizophrenia ( 31447353)
- Brain morphology (MOSTest) ( 32665545)
- Cholesterol, total ( 24097068 20686565)
- Fasting glucose ( 33402679)
- Hemoglobin ( 32888494)
- Hip circumference adjusted for BMI ( 34021172)
- LDL cholesterol ( 24097068 20686565)
- LDL cholesterol levels ( 28334899)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
- Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
- Male-pattern baldness ( 28196072)
- Metabolite levels ( 23823483)
- PR interval ( 32439900)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Total cholesterol levels ( 28334899)
- Urate levels ( 31578528)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172)
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Interacting Genes |
61 interacting genes:
APAF1
APP
ATM
BARD1
BRCA1
BRD2
BTBD1
BTBD2
BUB3
CASP3
CASP6
CDK8
CKAP5
CSNK2A1
CSNK2A2
DDB2
ELK3
ERCC8
ERG
FSHR
GEMIN4
IL7R
IRF4
IRF8
IRF9
JAK1
JUN
KMT2A
LIG4
LSM4
MDM2
NCL
NCOA6
PDE10A
PIAS4
PPP2R2B
PRB1
PRKDC
PYGM
RBL1
RBL2
RCVRN
SF3B1
SFPQ
SNRNP70
SNW1
SRPK2
SRSF1
SRSF11
SUMO1
SYMPK
TARBP2
TDP1
TOPORS
TP53
TRIM32
TUBD1
U2AF2
UBE2I
XRCC5
XRCC6
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3 interacting genes:
CASP3
TOP1
WDR3
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Entrez ID |
7150 |
10846 |
HPRD ID |
00535 |
17828 |
Ensembl ID |
ENSG00000198900
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ENSG00000112541
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Uniprot IDs |
P11387
Q9BVT2
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A0A1B1UZQ1
A0A1B1UZR0
Q9Y233
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PDB IDs |
1A31
1A35
1A36
1EJ9
1K4S
1K4T
1LPQ
1NH3
1R49
1RR8
1RRJ
1SC7
1SEU
1T8I
1TL8
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1LRB
2OUN
2OUP
2OUQ
2OUR
2OUS
2OUU
2OUV
2OUY
2WEY
2Y0J
2ZMF
3SN7
3SNI
3SNL
3UI7
3UUO
3WI2
3WS8
3WS9
3WYK
3WYL
3WYM
4AEL
4AJD
4AJF
4AJG
4AJM
4BBX
4DDL
4DFF
4FCB
4FCD
4HEU
4HF4
4LKQ
4LLJ
4LLK
4LLP
4LLX
4LM0
4LM1
4LM2
4LM3
4LM4
4MRW
4MRZ
4MS0
4MSA
4MSC
4MSE
4MSH
4MSN
4MUW
4MVH
4P0N
4P1R
4PHW
4TPM
4TPP
4WN1
4XY2
4YQH
4YS7
4ZO5
5AXP
5AXQ
5B4K
5B4L
5C1W
5C28
5C29
5C2A
5C2E
5C2H
5DH4
5DH5
5EDE
5EDG
5EDH
5EDI
5I2R
5K9R
5UWF
5XUI
5XUJ
5ZNL
6IJH
6IJI
6KDX
6KDZ
6KE0
6KO0
6KO1
6KZE
6MSA
6MSC
7BPI
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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