CLDN5 and CYB561A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDN5	CYB561A3
Description		claudin 5	cytochrome b561 family member A3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Paranode Region Of Axon Schmidt-Lanterman Incisure Tight Junction	Nucleolus Lysosomal Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity
	Biological Process	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Blood-brain Barrier Myelination Negative Regulation Of Vascular Permeability Response To Ethanol Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier	Cellular Iron Ion Homeostasis Transmembrane Transport
Pathways		Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1	23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31
Entrez ID		7122	220002
HPRD ID		03654	11316
Ensembl ID		ENSG00000184113	ENSG00000162144
Uniprot IDs		D3DX19 O00501	F5H1Q2 Q8NBI2
PDB IDs
Enriched GO Terms of Interacting Partners?
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