TCF12 and CRCP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TCF12	CRCP
Description		transcription factor 12	CGRP receptor component
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Nuclear Speck Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Regulator Complex	Acrosomal Vesicle Nucleoplasm RNA Polymerase III Complex Cytosol Plasma Membrane DNA Polymerase III Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding CAMP Response Element Binding BHLH Transcription Factor Binding SMAD Binding Protein Heterodimerization Activity E-box Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Calcitonin Gene-related Peptide Receptor Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Immune Response Nervous System Development Muscle Organ Development Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Neuropeptide Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Myogenesis Myogenesis RUNX1 regulates transcription of genes involved in differentiation of HSCs NGF-stimulated transcription NGF-stimulated transcription	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein B levels ( 32203549) Body mass index ( 28892062) Glaucoma (primary open-angle) ( 33627673 29891935) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Male-pattern baldness ( 28196072) Mean platelet volume ( 32888494 27863252) Triglyceride levels ( 32154731) Type 2 diabetes ( 30297969)	Aortic root size ( 21223598) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		86 interacting genes: ACTB ADAM10 ARL16 ARMC8 ASCL3 ASCL4 BCL2L10 BMERB1 BMF C1orf109 CDKN2C CFAP206 CKS1B CLCNKA CRCP CREBBP DDX6 DGCR6 EDRF1 EP300 EXOC8 FERD3L FIGLA FRMD6 GRB7 HAND1 HAND2 HEXIM2 HOPX ID1 ID2 ID3 LAMTOR5 LNX1 LYSMD1 MAPK6 MAPKBP1 MLLT6 MORN4 MSC MSGN1 MYF6 MYO15B NAGK NEK6 NEUROD1 NEUROG1 NEUROG3 NGLY1 NHLH2 OLIG3 OSGIN1 PIN1 PRKAB2 PRSS23 PSMA1 PTF1A QARS1 RBM8A RNASEL RSL24D1 RUNX1T1 SCG3 SLC12A1 SLC24A1 SOX10 SOX8 SPG21 SPTBN5 SRI STAT5A STK16 TAF4 TAL2 TBC1D21 TBP TCF21 TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28 WTAP YKT6 ZNF688	9 interacting genes: AGR2 CALCRL DYNLRB1 GSC2 LRIF1 POLR3H TCF12 VAV2 ZMIZ2
Entrez ID		6938	27297
HPRD ID		02725	12089
Ensembl ID		ENSG00000140262	ENSG00000241258
Uniprot IDs		A0A024R5T1 A0A024R5Z0 F5GY10 Q99081	A0A024RDL0 O75575
PDB IDs		2KNH 4JOL	7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59
Enriched GO Terms of Interacting Partners?
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