TAL2 and LMO1

Number of citations of the paper that reports this interaction (PubMedID 7957052)
69

Data Source:
BioGRID (two hybrid)
HPRD (in vivo)

		TAL2	LMO1
Description		TAL bHLH transcription factor 2	LIM domain only 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Post-embryonic Development Thalamus Development Midbrain Development Multicellular Organism Growth	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of T Cell Homeostatic Proliferation
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Menarche (age at onset) ( 19448620) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Alcohol consumption ( 23743675) Body mass index ( 31888951 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Diastolic blood pressure ( 27618447) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting glucose ( 34059833) Height ( 31562340) Malaria ( 31844061) Neuroblastoma ( 22941191 21124317) Offspring birth weight ( 31043758) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Response to selenium supplementation (change in plasma selenium concentration) ( 33382417) Restless legs syndrome ( 33239738) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 27618447)
Interacting Genes		11 interacting genes: CBFA2T2 CDK6 HLA-DQA1 LMO1 LMO2 MAPK3 PCBD2 RUNX1T1 TCF12 TCF3 TCF4	122 interacting genes: ABI1 ABI2 ADAMTSL4 AKAP9 AKNA ASB15 BANP BCAS2 BCL11A BHLHB9 BIVM BLZF1 BNC2 BYSL CARD9 CBY2 CCDC33 CCDC88B CDCA7L CDX4 CEP170P1 CEP44 CEP57L1 CHCHD3 DDIT4L ERBIN EVI5 FBXO16 GABPB1 GAS8 GATA3 GOLGA2 GPATCH2L HDX HGS HMBOX1 HMG20A HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IKZF3 ISY1 KANK2 KCTD1 KIAA1328 KRBOX4 KRT16 KRT40 KRT75 LDB1 LDB2 LPXN LYL1 LZTS1 LZTS2 MAD1L1 MBD3L1 MEOX2 MISP MSS51 NAGK NDUFA7 NHLH1 NTAQ1 NUTM1 PHC2 PICK1 POLR3GL PPP1R13B PRDM6 PSMB1 PTPN3 PXN RBBP8 RCN1 REL SAXO1 SNTA1 SOX5 SPG21 SYTL4 TADA2A TAL1 TAL2 TASOR2 TCF4 TCP10L TFIP11 TLE5 TRIM27 TRIM35 TRIM54 TSC22D4 UFSP2 UHMK1 UNKL UTP14A VBP1 WASHC1 ZBTB43 ZBTB8B ZCCHC12 ZFP90 ZNF143 ZNF177 ZNF19 ZNF219 ZNF24 ZNF354C ZNF417 ZNF460 ZNF511 ZNF526 ZNF559-ZNF177 ZNF620 ZNF641 ZNF688 ZNF76 ZNF84
Entrez ID		6887	4004
HPRD ID		01735	01738
Ensembl ID		ENSG00000186051	ENSG00000166407
Uniprot IDs		Q16559	E9PK83 P25800
PDB IDs
Enriched GO Terms of Interacting Partners?
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