TAL1 and NCAPG2

Number of citations of the paper that reports this interaction (PubMedID 14729962)
6

Data Source:
HPRD (two hybrid)

		TAL1	NCAPG2
Description		TAL bHLH transcription factor 1, erythroid differentiation factor	non-SMC condensin II complex subunit G2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex	Condensin Complex Nucleus Nucleoplasm Membrane Nuclear Speck
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Histone Deacetylase Binding Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding E-box Binding	Protein Binding Enzyme Activator Activity Transmembrane Receptor Protein Tyrosine Kinase Inhibitor Activity Histone Deacetylase Regulator Activity Methylated Histone Binding BHLH Transcription Factor Binding Transcription Regulator Inhibitor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Locomotory Behavior Spinal Cord Association Neuron Differentiation Hemopoiesis Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Positive Regulation Of Protein-containing Complex Assembly Embryonic Hemopoiesis Megakaryocyte Development Regulation Of Cell Population Proliferation Erythrocyte Maturation Cell Fate Commitment Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Division Astrocyte Fate Commitment Definitive Hemopoiesis Hemangioblast Cell Differentiation Hematopoietic Stem Cell Differentiation Regulation Of Mast Cell Differentiation Regulation Of Stem Cell Population Maintenance	Mitotic Sister Chromatid Segregation Inner Cell Mass Cell Proliferation Transcription By RNA Polymerase II Regulation Of Gene Expression Erythrocyte Differentiation Chromosome Condensation Regulation Of Histone Deacetylation Cell Division Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Signaling Receptor Activity
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Transcriptional regulation of granulopoiesis	Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494)	Hearing loss in noise exposure ( 33242228) Metabolite levels ( 23823483) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Number of sexual partners ( 30643258) Plateletcrit ( 32888494) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Testicular germ cell tumor ( 28604732)
Interacting Genes		24 interacting genes: CHD3 DRG1 ELSPBP1 EP300 GATA1 GATA2 GATA3 HDAC1 HOXB9 KAT2B KDM1A LMO1 LMO2 MAPK3 NCAPG2 PRKCQ SIN3A SKP2 SP1 STOML2 STUB1 TCF3 TCF4 ZHX1	1 interacting genes: TAL1
Entrez ID		6886	54892
HPRD ID		01753	10539
Ensembl ID		ENSG00000162367	ENSG00000146918
Uniprot IDs		P17542 Q16509	B3KRQ2 Q86XI2
PDB IDs		2YPA 2YPB
Enriched GO Terms of Interacting Partners?
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