TAF6 and TAF8

Number of citations of the paper that reports this interaction (PubMedID 14580349)
21

Data Source:
HPRD (in vivo, in vitro)

		TAF6	TAF8
Description		TATA-box binding protein associated factor 6	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	SAGA Complex Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex MLL1 Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated RNA Polymerase II Preinitiation Complex Assembly	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Regulation Of Fat Cell Differentiation Maintenance Of Protein Location In Nucleus
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 33491795) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		25 interacting genes: AHR APP BANP CIITA GTF2E1 H3-4 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 PIH1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9	15 interacting genes: H3-4 KPNA2 KPNB1 RSPH9 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9 TCTE1
Entrez ID		6878	129685
HPRD ID		11807	18167
Ensembl ID		ENSG00000106290	ENSG00000137413
Uniprot IDs		A4D299 P49848	Q7Z7C8
PDB IDs		5FUR 6F3T 6MZC 6MZD 6MZL 6MZM	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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