SUOX and PIH1D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SUOX	PIH1D2
Description		sulfite oxidase	PIH1 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Cytoplasm R2TP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding	Protein Binding Small GTPase Binding
	Biological Process	Sulfur Compound Metabolic Process	Box C/D SnoRNP Assembly RRNA Processing
Pathways		Sulfide oxidation to sulfate
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		82 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CAP1 CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT4 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MRPS35 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RNF41 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TAS2R7 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC	69 interacting genes: ANKRD11 BAG3 BANP CBLL2 CBX8 CCNL2 CDC23 CDCA8 CDKL3 CFAP206 COMMD3 CT55 CTAG1A CTAG1B DES DPH3 DSCAM EIF4A2 EXOSC5 FRS3 GFAP GMCL1 GPRASP2 HES7 HSF4 IGF2BP3 IQUB ITGB3BP KRTAP12-2 KRTAP12-4 LAP3 LMNB1 MCCD1 MDFI MED20 MISP MRFAP1L1 MVP NFIL3 NHSL2 NOTO NTAQ1 NXF1 PBX4 PLEKHJ1 POLR1C PRDM6 PRMT3 RALA REL RSPO4 SDCBP SERTAD1 SLPI SPRED1 SSX3 SUOX TAF6 TASOR2 TBATA TCEA2 TNNI1 TTC23 ZBTB1 ZMAT5 ZNF185 ZNF417 ZNF438 ZNF688
Entrez ID		6821	120379
HPRD ID		06055	14021
Ensembl ID		ENSG00000139531	ENSG00000150773
Uniprot IDs		A0A024RB79 P51687	Q8WWB5
PDB IDs		1MJ4
Enriched GO Terms of Interacting Partners?
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