SSTR1 and SST

Number of citations of the paper that reports this interaction (PubMedID 1346068)
76

Data Source:
HPRD (in vivo)

		SSTR1	SST
Description		somatostatin receptor 1	somatostatin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Region Extracellular Space Neuronal Cell Body Synapse
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding	Hormone Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Glutamate Receptor Signaling Pathway Neuropeptide Signaling Pathway Spermatogenesis Negative Regulation Of Cell Population Proliferation Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Estradiol Stimulus Cellular Response To Leukemia Inhibitory Factor	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Heat Response To Xenobiotic Stimulus Response To Acidic PH Regulation Of Cell Migration Response To Amino Acid Response To Steroid Hormone
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands
Drugs		Pasireotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)	Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)
Interacting Genes		6 interacting genes: AKAP6 CORT PRMT5 SNTA1 SST SSTR5	7 interacting genes: FXR1 PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6751	6750
HPRD ID		01673	08920
Ensembl ID		ENSG00000139874	ENSG00000157005
Uniprot IDs		P30872 Q86SW9	P61278
PDB IDs			1P2W 2MI1
Enriched GO Terms of Interacting Partners?
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