SPTAN1 and GAP43

Number of citations of the paper that reports this interaction (PubMedID 10521589)
7

Data Source:
HPRD (in vivo)

		SPTAN1	GAP43
Description		spectrin alpha, non-erythrocytic 1	growth associated protein 43
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Spectrin Microtubule Cytoskeleton Membrane Cell Junction Cortical Actin Cytoskeleton Specific Granule Lumen Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome Extracellular Vesicle Tertiary Granule Lumen	Cytoplasm Plasma Membrane Postsynaptic Density Dendrite Filopodium Membrane Growth Cone Membrane Perikaryon GABA-ergic Synapse
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Cadherin Binding Actin Filament Binding	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament Capping	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Regulation Of Postsynaptic Specialization Assembly
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport RHOU GTPase cycle RHOV GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	L1CAM interactions
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971)	Borderline personality disorder ( 28632202) Breast size ( 22747683) Eye color ( 33692100) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)
Interacting Genes		60 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB AKIP1 ANK1 C5 CAPN1 CASP3 CASP7 CEP63 CNTRL CREBBP CTNNA1 DDX24 DES EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D KALRN KARS1 MAPK6 NEFL PDE4D PIN4 PLEC PLEKHA5 PRKCB PTEN PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SPTBN2 SPTBN4 SRC STAT1 SUMO2 SYN1 TAF1 TANC1 TES TRAF1 TSSC4 ZNF333	10 interacting genes: CALM1 CD47 CSNK2A1 ELAVL4 LOX PLCD1 PRKCB PRKCD RABEP1 SPTAN1
Entrez ID		6709	2596
HPRD ID		01684	01198
Ensembl ID		ENSG00000197694	ENSG00000172020
Uniprot IDs		A0A384P5S9 Q13813	P17677 Q5U058
PDB IDs		2FOT 3F31 3FB2 5FW9 5FWB 5FWC 6ZEH
Enriched GO Terms of Interacting Partners?
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