BPHL and ESRRG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BPHL	ESRRG
Description		biphenyl hydrolase like	estrogen related receptor gamma
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane	Chromatin Nucleoplasm
	Molecular Function	Alpha-amino-acid Esterase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Zinc Ion Binding AF-2 Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process Response To Toxic Substance	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis
Pathways		POLB-Dependent Long Patch Base Excision Repair Phase I - Functionalization of compounds	Nuclear Receptor transcription pathway
Drugs		L-tyrosinamide	Troglitazone Diethylstilbestrol Tamoxifen Cholic Acid Afimoxifene 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE p-Cumylphenol Bisphenol A Bisphenol Z Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate
Diseases
GWAS		Left-handedness ( 32989287)	Adventurousness ( 30643258) Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Adverse response to drug ( 30420678) Alcohol consumption ( 23743675) Breast cancer ( 29059683) Cardiac hypertrophy ( 21348951) Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761) Depressive symptom (anhedonia) (ordinal trait) ( 31530331) Dialysis-related mortality ( 21546767) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Energy expenditure (24h) ( 28476931) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Hematocrit ( 32888494) Hemoglobin ( 32888494) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) LDL cholesterol levels in HIV infection ( 33109212) Major depressive disorder ( 23377640) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Optic nerve measurement (cup area) ( 20395239) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Sleep duration ( 25469926) Smoking status (ever vs never smokers) ( 30643258) Tea consumption ( 31046077) Weight ( 28552196)
Interacting Genes		1 interacting genes: ESRRG	59 interacting genes: ADCY4 APP ARHGEF15 ATM BPHL C22orf23 CALM1 CAMK2G CCDC33 DAXX DEUP1 DUT EBP EFHC2 ESRRA ESRRB EXOSC7 FAM107A FAM9A FASTK HGS HIF1A KIFC3 LRRK2 MARK1 MCC MEOX2 MFHAS1 MRM1 NCOA1 NR0B1 NR0B2 NRIP1 NUP160 PAX6 PNRC1 PNRC2 POMC PPARGC1A PPARGC1B PROX1 PSMC5 RBIS REL RINT1 SHTN1 SNIP1 SP1 SRA1 SRPK1 SUMO1P1 TLE1 TNNI1 TNNI2 TRERF1 TULP3 UBL7 VAX1 ZNF438
Entrez ID		670	2104
HPRD ID		04403	04274
Ensembl ID		ENSG00000137274	ENSG00000196482
Uniprot IDs		A0A024QZY0 Q49AI2 Q86W56 Q86WA6	B7Z5E9 C0SQ93 F1D8R5 F1D8R6 P62508
PDB IDs		2OCG 2OCI 2OCK 2OCL 4A0D 4B1G 4B1H 4B1I 4B1J 5A7R 5LHB 6HH6 6HMK 6HML 6HMM 6HMN 6O9X 6O9Y 6OA0 6OA1 6OA3 6OAK 6OAL	1KV6 1TFC 1VJB 2E2R 2EWP 2GP7 2GPO 2GPP 2GPU 2GPV 2P7A 2P7G 2P7Z 2ZAS 2ZBS 2ZKC 5YSO 6A6K 6I61 6I62 6I63 6I64 6I65 6I66 6I67 6K3N 6KNR
Enriched GO Terms of Interacting Partners?
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