SPRR1A and GLIS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPRR1A	GLIS1
Description		small proline rich protein 1A	GLIS family zinc finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol	Nucleus
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Keratinization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Cerebrospinal fluid AB1-42 levels ( 28247064) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Glaucoma (primary open-angle) ( 33627673) Hand grip strength ( 29691431 29313844) Mitral valve prolapse ( 26301497) Monobrow ( 27182965) Nicotine use ( 23942779) Non-substance related behavioral disinhibition ( 23942779) Nose size ( 27182965) Refractive error ( 32231278) Response to statin therapy ( 20339536)
Interacting Genes		3 interacting genes: ACTA1 FCER1G GLIS1	13 interacting genes: ARNT CDK6 CDKN2A GLIS2 LATS2 MYC NFIC RELA SOX3 SPRR1A TCF3 TEAD2 ZDHHC23
Entrez ID		6698	148979
HPRD ID		01647	13581
Ensembl ID		ENSG00000169474	ENSG00000174332
Uniprot IDs		P35321	A0A0D9SEX9 Q8NBF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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