SPARC and CPEB2

Number of citations of the paper that reports this interaction (PubMedID 22157746)
35

Data Source:
BioGRID (two hybrid)

		SPARC	CPEB2
Description		secreted protein acidic and cysteine rich	cytoplasmic polyadenylation element binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Cytoplasm Mitochondrion Plasma Membrane Cell Surface Nuclear Matrix Platelet Alpha Granule Platelet Alpha Granule Membrane Platelet Alpha Granule Lumen Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix Endocytic Vesicle Lumen Glutamatergic Synapse	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Collagen Binding Extracellular Matrix Binding	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding
	Biological Process	Ossification Negative Regulation Of Endothelial Cell Proliferation Heart Development Response To Gravity Response To Lead Ion Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Cell Morphogenesis Lung Development Response To Lipopolysaccharide Response To L-ascorbic Acid Response To Cytokine Wound Healing Response To Peptide Hormone Response To Ethanol Response To Cadmium Ion Inner Ear Development Anatomical Structure Development Regulation Of Synapse Organization Response To Glucocorticoid Response To CAMP Response To Calcium Ion	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation
Pathways		Platelet degranulation Nuclear signaling by ERBB4 ECM proteoglycans Scavenging by Class H Receptors
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Stroke ( 32693751)	Cognitive flexibility ( 30134085) Triglyceride levels ( 32203549) Type 2 diabetes ( 33479058)
Interacting Genes		24 interacting genes: COL13A1 COL1A1 COL1A2 COL2A1 COL3A1 COL5A1 CPEB2 CTSK FN1 HDAC5 HSPG2 PDGFA PDGFB PLAT PLG SDC2 TGFB1 TGM2 THBS1 TNC UBQLN1 VEGFA XRCC6 ZNF579	22 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 CC2D2A COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A
Entrez ID		6678	132864
HPRD ID		01631	16744
Ensembl ID		ENSG00000113140	ENSG00000137449
Uniprot IDs		P09486	A0A5K1VW61 A0A5K1VW71 A0A5K1VW79 A0A5K1VW93 Q7Z5Q1
PDB IDs		1BMO 1NUB 1SRA 2V53
Enriched GO Terms of Interacting Partners?
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