SP4 and SERF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SP4	SERF2
Description		Sp4 transcription factor	small EDRK-rich factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Nucleus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Molecular_function
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Destabilization
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 29348612) Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Bipolar disorder ( 31043756) General cognitive ability ( 29844566) LDL cholesterol levels ( 32203549) Major depressive disorder ( 20125088) Major depressive disorder (broad) ( 20038947) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227) Multisite chronic pain ( 33830993 31194737) Plateletcrit ( 32888494) Schizophrenia ( 30285260) Temporomandibular joint disorder ( 28081371)
Interacting Genes		35 interacting genes: ADAM15 AP1M1 ATXN7L1 BANP CIB3 COL8A1 E2F1 ELK3 FOXP2 GTF2A1 HIVEP1 HYPK ITGB8 LMO3 LNX1 MCRS1 NFYC NKX3-1 NRF1 PELI2 PNKP POGZ POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E PRSS59P SERF2 SP1 SPANXN2 SPANXN3 VEZF1 ZBTB7A	17 interacting genes: BOLL CHD3 DAB1 GC KRTAP10-3 MDFI NELFCD PSMA3 PSME3 PTPN11 QKI RBPMS RHOXF2 SP4 THAP1 UPF2 WT1
Entrez ID		6671	10169
HPRD ID		02764	05447
Ensembl ID		ENSG00000105866	ENSG00000140264
Uniprot IDs		A0A3B3IRW4 Q02446 Q32M51	P84101
PDB IDs
Enriched GO Terms of Interacting Partners?
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