SMARCE1 and MRFAP1L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SMARCE1	MRFAP1L1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	Morf4 family associated protein 1 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	Protein Binding Identical Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 31959851 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		90 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CCDC183 CCHCR1 CDR2 CEP170P1 CEP63 CEP70 CYSRT1 DISC1 EPS8 ESR1 ESR2 EXOC4 EXOC7 FAM217B FSD2 GATA1 GOLGA2 GOLGA6L9 GRIPAP1 IFT74 IFT88 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT14 KRT15 KRT16 KRT19 KRT27 KRT31 KRT34 KRT35 KRT37 KRT39 KRT40 KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP6-3 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 OGT OIP5 PGR PRMT5 PSMC6 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TEX12 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1 VPS52	47 interacting genes: ABI1 ABI2 ABI3 BYSL C1orf216 C3orf62 CAGE1 CAVIN3 CDK2AP1 CDK2AP2 CENPK CEP44 CNOT7 CSPP1 EIF2B2 GAS8 GTF2IRD1 HGS HTT IHO1 JAKMIP1 LMO2 LNX1 LNX2 MEOX2 MORF4L1 MORF4L2 MRFAP1 NTAQ1 PIH1D2 PIK3R2 PSMA1 RADIL RDM1 SDCBP SFR1 SMARCE1 SMU1 SYCE1 TCF4 TEX11 TMEM126B TSNAX TXN2 UBTD1 ZDHHC17 ZNF417
Entrez ID		6605	114932
HPRD ID		04382	15162
Ensembl ID		ENSG00000073584	ENSG00000178988
Uniprot IDs		A0A024R1S7 Q969G3	A0A075DDR2 Q96HT8
PDB IDs		6LTH 6LTJ 7CYU
Enriched GO Terms of Interacting Partners?
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