SLC16A1 and CRBN

Number of citations of the paper that reports this interaction (PubMedID 27294876)
46

Data Source:
BioGRID (pull down, pull down)

		SLC16A1	CRBN
Description		solute carrier family 16 member 1	cereblon
Image
GO Annotations	Cellular Component	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Cell Junction Intracellular Membrane-bounded Organelle Synapse Extracellular Exosome	Nucleus Cytoplasm Cytosol Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Mevalonate Transmembrane Transporter Activity Symporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity Organic Cyclic Compound Binding	Protein Binding Transmembrane Transporter Binding Metal Ion Binding
	Biological Process	Lipid Metabolic Process Centrosome Cycle Monocarboxylic Acid Transport Mevalonate Transport Response To Food Plasma Membrane Lactate Transport Glucose Homeostasis Regulation Of Insulin Secretion Behavioral Response To Nutrient Cellular Response To Organic Cyclic Compound Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport	Protein Ubiquitination Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Locomotory Exploration Behavior Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Large Conductance Calcium-activated Potassium Channel Activity
Pathways		Basigin interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Pyruvate metabolism	Potential therapeutics for SARS
Drugs		Pyruvic acid Mersalyl	Lenalidomide Thalidomide Pomalidomide
Diseases
GWAS		Macular thickness ( 30535121) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Refractive error ( 32231278)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Immune response to smallpox vaccine (IL-6) ( 22542470) Knee osteoarthritis ( 27696742) Malaria ( 31844061) Restless legs syndrome ( 29029846) White blood cell count (basophil) ( 29403010 27863252) White matter integrity ( 23218918)
Interacting Genes		3 interacting genes: AGTR1 BSG CRBN	38 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 CUL4B CYP19A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A KPNB1 MISP OSR1 OSR2 PAK5 PIK3R3 PRKAG1 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91
Entrez ID		6566	51185
HPRD ID		02816	16750
Ensembl ID		ENSG00000155380	ENSG00000113851
Uniprot IDs		A0A024R0H1 B4DKS0 P53985	Q96SW2
PDB IDs		6LYY 6LZ0 7CKO 7CKR 7DA5	4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G 6UML 6XK9 7BQU 7BQV
Enriched GO Terms of Interacting Partners?
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