SLC12A4 and ATF7IP

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		SLC12A4	ATF7IP
Description		solute carrier family 12 member 4	activating transcription factor 7 interacting protein
Image
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Synapse	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body
	Molecular Function	Protein Binding Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways		Cation-coupled Chloride cotransporters	PKMTs methylate histone lysines
Drugs		Potassium chloride Bumetanide
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340 33713608) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		10 interacting genes: AP3M1 ATF7IP CNFN CYSRT1 KRTAP12-2 KRTAP19-2 MB21D2 MTNR1B TMEM102 ZNF655	70 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		6560	55729
HPRD ID		04987	09811
Ensembl ID		ENSG00000124067	ENSG00000171681
Uniprot IDs		B4DF30 Q9UP95	A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6
PDB IDs		6KKR 6KKT 6KKU	2RPQ
Enriched GO Terms of Interacting Partners?
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