C8orf33 and TAOK1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		C8orf33	TAOK1
Description		chromosome 8 open reading frame 33	TAO kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Alpha-tubulin Binding Protein Serine/threonine Kinase Activator Activity Tau Protein Binding Beta-tubulin Binding Tau-protein Kinase Activity Protein Serine Kinase Activity
	Biological Process		MAPK Cascade Microtubule Cytoskeleton Organization DNA Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Microtubule Depolymerization Mitotic G2 DNA Damage Checkpoint Signaling Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Regulation Of Cytoskeleton Organization Neuron Cellular Homeostasis Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Protein Serine/threonine Kinase Activity Execution Phase Of Apoptosis Positive Regulation Of Protein Acetylation
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS			Body shape index ( 34021172) Mean platelet volume ( 22139419 24026423 19110211 19820697 32888494 22423221 27863252) Platelet count ( 22139419 29066854 32888494) Red cell distribution width ( 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		49 interacting genes: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DISC1 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MAPK8IP2 MCC MDFI MRFAP1 NACC1 NGEF NOL7 PI4KA PICK1 PNMA1 RASSF1 SF3B2 TAOK1 TNIP1 TRIM23 TRIM41 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331 ZNF526	8 interacting genes: C8orf33 CSNK1E DYNC1I1 GEMIN7 MAP2K3 MARK1 NUFIP2 WT1
Entrez ID		65265	57551
HPRD ID		07951	15467
Ensembl ID		ENSG00000182307	ENSG00000160551
Uniprot IDs		Q9H7E9	A0A024QZ70 Q7L7X3
PDB IDs
Enriched GO Terms of Interacting Partners?
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