IKZF4 and TCAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IKZF4	TCAF1
Description		IKAROS family zinc finger 4	TRPM8 channel associated factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Protein-containing Complex	Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding	Protein Binding Transmembrane Transporter Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization	Regulation Of Anion Channel Activity Negative Regulation Of Cell Migration Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Anion Channel Activity
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Alopecia areata ( 20596022 25608926) Anorexia nervosa ( 28494655) Asthma ( 21804548 31959851 32700739 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autoimmune traits (pleiotropy) ( 30572963) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cognitive function ( 25644384) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Type 1 diabetes ( 21829393 25751624 18198356) Vitiligo ( 27723757 22561518)
Interacting Genes		20 interacting genes: CDC7 CHD4 CSNK1D FHL2 FOXP3 HDAC2 IKZF1 IKZF2 IKZF3 IKZF5 MCRS1 MOB1A MOB3C NFKBIA NRG1 SIN3A SIN3B TCAF1 TCEA2 TXK	37 interacting genes: BIRC2 CAMK2A CEP70 CNKSR1 COIL CYSRT1 DISC1 EFEMP2 IKZF3 IKZF4 KRTAP1-3 KRTAP10-8 KRTAP13-2 KRTAP6-3 MAD1L1 MID2 NBPF19 NFYA NOTCH2NLA PRDM14 PRDM6 RBAK SCYL3 SF3B4 SPRY2 TAX1BP1 TCF3 TFIP11 TRAF2 TRIM42 TRIM54 TRIP6 UBC ZNF143 ZNF24 ZNF263 ZNF592
Entrez ID		64375	9747
HPRD ID		05874	13813
Ensembl ID		ENSG00000123411	ENSG00000198420
Uniprot IDs		Q9H2S9	B4DST7 Q9Y4C2
PDB IDs		2MA7
Enriched GO Terms of Interacting Partners?
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