CXCR5 and PLS3

		CXCR5	PLS3
Description		C-X-C motif chemokine receptor 5	plastin 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Cytoplasm Cytosol Actin Filament Plasma Membrane Actin Filament Bundle
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding	Calcium Ion Binding Actin Filament Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Leukocyte Chemotaxis Positive Regulation Of Cytokinesis B Cell Activation Lymph Node Development Cell Chemotaxis Chemokine-mediated Signaling Pathway	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 30929738 34103634 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Celiac disease and Rheumatoid arthritis ( 26546613) Follicular lymphoma ( 25279986) Human herpesÂ virusÂ 7 U14Â antibodyÂ levels ( 33204752) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 24076602 21833088) Post-bronchodilator lung function in asthma (FVC) ( 32989782) Primary biliary cholangitis ( 28425483 21399635 26394269) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 24390342) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 32771030) Trunk fat mass ( 28552196) Vitiligo ( 22951725)	Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)
Interacting Genes		7 interacting genes: ARCN1 CBL CXCL13 DPAGT1 MRE11 PLS3 TLK1	17 interacting genes: ACRV1 APP ASGR1 ATXN2 CUL4B CXCR5 FRYL LRCH2 NRSN1 OGT PTPN5 TGIF2 TRPC5 TSPAN32 WFDC2 ZBTB33 ZNF195
Entrez ID		643	5358
HPRD ID		03367	02133
Ensembl ID		ENSG00000160683	ENSG00000102024
Uniprot IDs		A0N0R2 A8K647 P32302 Q2YD84	B4DPW9 P13797
PDB IDs			1AOA 1WJO
Enriched GO Terms of Interacting Partners?
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